This retrospective analysis finding that treatment with surgical resection and/or radiotherapy is associated with increased OS constitutes the largest cohort of patients with aggressive vertebral hemangiomas to date. Cox survival analysis further revealed improved OS in patients who received surgical treatment and higher radiation dose. The most common symptom reported by patients with symptomatic hemangiomas is pain at the site of the tumor. These tumors are present in about 10 of people and typically do not cause symptoms or require treatment. Multivariate analysis revealed associations between decreased OS and advanced age (>65 years) and presence of metastasis. Spinal Hemangioma is an often-benign spinal tumor that develops from the blood vessels. Administered treatments included partial surgical resection (n = 17), radical resection (n = 14), chemotherapy (n = 34), and radiotherapy (n = 56). Survival curves for comparative visualization of demographic and treatment factors were generated using a semiparametric Cox approach.Ī cohort of 102 patients with histologically confirmed spinal hemangiomas was identified in the database. A Cox proportional hazards model was used to perform multivariate regression analysis of survival. The National Cancer Database was queried for spinal hemangiomas between 20. This study sought to investigate current trends affecting overall survival (OS) using the National Cancer Database (NCDB) and to formulate treatment recommendations. Treatment for these aggressive variants is controversial, often involving surgery, chemotherapy, and/or radiotherapy. Although these tumors are most frequently benign and asymptomatic, they can rarely exhibit aggressive growth and invasion into neighboring structures. Spinal hemangiomas are common primary tumors of the vertebrae.
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